CCR-HM08V-100μg / 詢價(jià)
CCR-HM08V-100μgx5 / 詢價(jià)
CCR-HM08V-100μgx10 / 詢價(jià)
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Human CCR8 VLP
Recombinant Human CCR8 VLP is expressed from HEK293.It contains Met1-Leu355 (It may have cross reaction with anti-His antibody) [Accession | P51685].
Human CCR8 Protein has a predicted MW of 44.06 kDa.
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
CCR-8; CMKBRL2; CKR-L1; GPR-CY6; GPRCY6; TER1; CCR8; CKRL1; CMKBR8; CD198; ChemR1; CKR-L1; CY6; TER-1; CDw198
(1) Berenguer J, Lagerweij T, Zhao XW, Dusoswa S, van der Stoop P, Westerman B, de Gooijer MC, Zoetemelk M, Zomer A, Crommentuijn MHW, Wedekind LE, López-López à, Giovanazzi A, Bruch-Oms M, van der Meulen-Muileman IH, Reijmers RM, van Kuppevelt TH, García-Vallejo JJ, van Kooyk Y, Tannous BA, Wesseling P, Koppers-Lalic D, Vandertop WP, Noske DP, van Beusechem VW, van Rheenen J, Pegtel DM, van Tellingen O, Wurdinger T. Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. J Extracell Vesicles. 2018 Mar 13;7(1):1446660.
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