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BCM-HM107 | 價(jià)格

BCM-HM107-100μg / 詢(xún)價(jià)

BCM-HM107-500μg / 詢(xún)價(jià)

BCM-HM107-500μgx2 / 詢(xún)價(jià)

Human BCMA/TNFRSF17 Protein

COA MSDS
產(chǎn)品信息（Product Info）
表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）

Recombinant Human BCMA/TNFRSF17 Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Met1-Ala54 [Accession | Q02223-1].

分子量大小（Molecular Weight）

The protein has a predicted MW of 7.51 kDa. Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.

純度（Purity）

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

內(nèi)毒素（Endotoxin）

Less than 0.1 EU per μg by the LAL method.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重構(gòu)方法（Reconstitution）

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存儲(chǔ)（Storage）

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

產(chǎn)品數(shù)據(jù)（Assay Data）
Bis-Tris PAGE
Human BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human BCMA is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human BCMA, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human BAFF, monomeric Fc Tag with the EC50 of 3.8ng/ml determined by ELISA. (QC Test)
 
Immobilized Human BCMA, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Avi Tag with the EC50 of 16.5ng/ml determined by ELISA.
 
Immobilized Human BCMA, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA.
背景（Background）

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

分子別名（Synonyms）

CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

文獻(xiàn)（References）

(1) Bossen C , Schneider P. BAFF, APRIL and their receptors: Structure, function and signaling[J]. Seminars in Immunology, 2006, 18(5):0-275.D

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.